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Hepatobiliary Scan
Photo by: Shanti.com
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Name of the Procedure: Hepatobiliary
Scan with and without GBEF.
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Indications: Assessment of how
hepatobiliary system functions, Evaluation of suspected
acute cholecystitis, Evaluation of common bile duct
obstruction, Evaluation of suspected chronic biliary tract
disorder, and Evaluation of congenital abnormalities of the
biliary tree.
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Contraindications: Retained burium,
Serum bilirubin level above 20 mg/dl may cause a
nondiagnostic examination due to poor hepatocellular
function. patient has just eaten a meal. Do not give
Kinevac if gallbladder and bowel activity are not seen
within 45-60 min.
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Patient Preparation: In order to
visualize the gallbladder, the patient must have fasted for
about 4 hrs prior to injection of the radiopharmaceutical.
If the patient has fasted for longer than 24 hrs, the
gallbladder may not fill with the tracer. In this case the
patient may be pretreated with sincalide.
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Radiopharmaceuticals: Tc-99m Choletec
is used. Administered dose will be 5-10 mCi given through an
IV (Intravenous injection). Inject the dose 4 hrs prior to
patient has fasted. Injection to imaging time is 5 min.
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Adjunct Pharmaceutical: none.
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Acquisition Parameters: Hepatobiliary
study, Collimator will be low-energy, all-purpose, parallel
hole. Images are obtained with 60 min dynamic and 30 min
post injection of Kinevac ( 0.02 mcg/kg in 10ml of normal
saline administered intravenously over 3-10 min) . Matrix is
64x64; Injection to imaging time is 5 min. positioning will
be supine. Photopeak selection is 140keV with 20% window.
Anterior view is acquired (1 frame /min) for the first 60
min, the last 30 min (post injection of Kinevac), and the
delayed images as needed. RLAT and RAO views can also be
obtained. You can not give Kinevac until the gallbladder and
the bowel activity are seen. When the gallbladder is not
seen within 40-60 min and cholecystitis is suspected, 3-4
hrs delayed images should be obtained, or morphine may be
employed intravenously ( 0.04mg/kg in 10 ml saline over 3-5
min). Delayed images, 18-24hrs may be necessary in some
cases (severely ill patients). If the patient is being
studied for a biliary leak, 2-4 hr delayed images will be
acquired, and decubitus views are employed.
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Computer Processing: First,
Hepatobiliary processing: Click general display and select
the patient’s name; click select all, and then click “all”;
click select predefined, and choose dynamic hepato; select
the first picture, and then choose select all from the edit
list; when all pictures are seen, choose deselect from the
edit list; type amount, the kind of radiopharmaceutical, and
the root of administration at the bottom of the first
picture; then print. The second part. Which is Gallbladder
processing, click processing tool on the top of the computer
screen; select gallbladder EF; select the patient’s name
choosing gallbladder EF; select the first picture; click OK;
then select the last picture; click OK; then click DONE;
draw region of interest (the gallbladder); click OK; When a
graph is seen move the arrow to the highest point, and click
OK; print the images.
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Normal Result: The size, shape, and
function of the gallbladder are normal. The ducts leading
from the liver and gallbladder to the small intestine
(duodenum) are not blocked or narrowed. Gallbladder
visualization within 45 min. GBEF > 35%
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Abnormal Result: The tracer may not
be removed normally from the bloodstream by the liver,
indicating possible liver disease. The radioactive tracer
may not reach the gallbladder, indicating inflammation or
blockage of the duct by a gallstone. The tracer may not
reach the beginning of the small intestine (duodenum),
indicating blockage of a bile duct by a stone, a tumor, or
inflammation of the pancreas. In addition, the gallbladder
may not contract normally. GBEF <35%

Picture is from: www.vh.org
This procedure manual was prepared
by:
A/Razaq H. Nuurre
Nuclear Medicine
Ohio, USA
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